Come on, just look at these guys. How can you resist?!
In late 2007, I had the unique pleasure of helping to build a site for Helping Hands. They train capuchin monkeys, known for their intelligence and dexterity, to accomplish everyday household tasks, then place them with people who are paralyzed or otherwise prohibitively disabled. The monkeys can play DVDs, open cabinets, operate remote controls, get drinks — all in all, totally amazing stuff.
I built the site to be as accessible and useful as possible, tested against Cynthia Says and Section 508, employing accesskeys for mouseless browsing, and built on top of WordPress for easy updates. Much of my original build is still online, though a good number of minor edits have taken place since launch.